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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:677.4 nTPM
HPA Brain:226.0 nTPM
GTEx:677.4 nTPM
FANTOM5:17.4 Scaled Tags Per Million
Pig:555.7 nTPM
Mouse:471.2 nTPM
Allen mouse:8.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

226.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 203.7
2411 Female, age 72, unknown 241.6
2828 Female, age 72, unknown 216.5
2586 Male, age 75, left hemisphere 213.8
1827 Male, age 72, unknown 207.4
1870 Female, age 42, unknown 200.2
2666 Male, age 74, left hemisphere 199.1
2019 Male, age 18, unknown 196.6
1830 Male, age 51, unknown 192.1
1833 Male, age 53, unknown 192.0
2219 Male, age 76, both hemispheres 177.9
Dorsal raphe nucleus
nTPM: 204.1
2016 Female, age 72, unknown 219.6
2298 Female, age 72, unknown 217.5
2750 Male, age 76, both hemispheres 206.1
1828 Male, age 53, unknown 194.2
2047 Male, age 72, unknown 182.9
Inferior colliculus
nTPM: 206.9
2097 Female, age 72, unknown 220.6
1890 Male, age 53, unknown 206.3
1848 Female, age 42, unknown 201.5
2849 Male, age 72, unknown 199.3
Median raphe nucleus
nTPM: 181.1
2220 Male, age 76, midline 181.1
Periaquaductal grey, anterior
nTPM: 204.3
2502 Female, age 75, unknown 227.4
1795 Male, age 51, unknown 197.8
1947 Male, age 18, unknown 187.8
Periaquaductal grey, dorsal
nTPM: 199.2
1840 Male, age 53, unknown 220.3
2464 Female, age 72, unknown 204.9
1831 Male, age 72, unknown 191.5
2850 Male, age 76, both hemispheres 179.9
Periaquaductal grey, lateral
nTPM: 187.0
2053 Male, age 18, unknown 215.5
2272 Male, age 74, both hemispheres 174.0
2140 Male, age 76, both hemispheres 171.5
Pretectal area
nTPM: 193.5
2007 Male, age 72, unknown 214.8
1817 Female, age 42, unknown 213.6
2316 Male, age 76, right hemisphere 206.8
1815 Male, age 53, unknown 201.9
1816 Male, age 51, unknown 198.9
2224 Female, age 72, unknown 190.3
2825 Male, age 18, unknown 189.1
2273 Male, age 74, both hemispheres 186.8
2407 Male, age 75, both hemispheres 177.7
1944 Female, age 72, unknown 174.8
2667 Female, age 75, unknown 174.0
Red nucleus
nTPM: 212.9
2503 Female, age 72, unknown 240.7
1865 Male, age 51, unknown 228.1
1821 Female, age 72, unknown 226.8
2769 Male, age 72, unknown 222.8
2584 Male, age 75, left hemisphere 216.9
2227 Male, age 72, unknown 216.7
2588 Male, age 74, left hemisphere 209.7
1904 Male, age 53, unknown 207.3
2725 Female, age 75, unknown 203.8
2785 Male, age 18, unknown 201.9
1954 Female, age 42, unknown 193.2
2823 Male, age 76, right hemisphere 187.1
Substantia nigra
nTPM: 226.0
1851 Male, age 51, unknown 264.0
2665 Male, age 74, both hemispheres 256.2
2409 Female, age 72, unknown 252.2
2699 Male, age 18, unknown 237.0
1916 Female, age 42, unknown 233.3
2241 Male, age 72, unknown 220.2
2590 Female, age 75, unknown 218.1
1889 Female, age 72, unknown 201.4
1941 Male, age 53, unknown 197.1
2583 Male, age 75, right hemisphere 181.0
Superior colliculus
nTPM: 205.5
2587 Male, age 74, left hemisphere 246.8
1796 Male, age 53, unknown 228.9
2668 Female, age 75, unknown 218.0
1995 Male, age 72, unknown 205.3
2261 Male, age 18, unknown 201.3
1913 Female, age 42, unknown 198.7
1839 Male, age 51, unknown 196.7
2664 Male, age 75, both hemispheres 195.0
2087 Female, age 72, unknown 188.5
1895 Male, age 76, right hemisphere 175.7
Ventral tegmental area
nTPM: 214.7
1915 Female, age 42, unknown 248.4
2223 Female, age 72, unknown 231.6
2410 Female, age 72, unknown 229.1
2021 Male, age 53, unknown 213.1
1942 Male, age 51, unknown 185.5
2218 Male, age 76, both hemispheres 180.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

677.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 677.4
Samples: 139

Max nTPM: 1673.2
Min nTPM: 342.0
Std nTPM: 215.5
Median nTPM: 642.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1673.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1429.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1365.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1293.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1097.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1086.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1064.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1053.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1033.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1016.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1007.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 969.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 959.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 921.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 916.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 916.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 894.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 891.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 884.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 881.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 879.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 876.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 866.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 841.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 837.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 829.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 826.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 826.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 816.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 814.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 813.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 798.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 788.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 783.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 773.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 768.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 756.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 755.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 753.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 753.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 750.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 747.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 736.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 733.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 732.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 731.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 726.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 722.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 721.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 717.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 715.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 713.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 712.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 709.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 708.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 698.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 698.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 697.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 693.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 670.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 668.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 664.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 663.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 660.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 659.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 655.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 650.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 648.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 647.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 642.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 639.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 637.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 627.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 626.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 622.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 622.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 617.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 609.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 601.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 600.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 596.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 595.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 595.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 589.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 585.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 581.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 578.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 575.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 573.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 568.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 566.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 566.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 555.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 551.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 547.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 545.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 545.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 544.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 543.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 542.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 542.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 540.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 539.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 539.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 532.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 531.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 528.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 524.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 523.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 514.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 514.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 502.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 499.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 498.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 493.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 492.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 481.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 476.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 475.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 466.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 464.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 463.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 458.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 456.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 449.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 448.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 447.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 445.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 440.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 426.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 426.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 410.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 401.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 387.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 387.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 383.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 375.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 368.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 342.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

17.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 17.4
FF:10158-103A5 76 years, female 17.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

555.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 535.7
Samples: 4

Max nTPM: 691.5
Min nTPM: 433.9
Sample A Female 691.5
Sample B Female 581.2
Sample C Male 433.9
Sample D Male 436.1
Midbrain
nTPM: 523.0
Samples: 4

Max nTPM: 751.3
Min nTPM: 367.6
Sample A Female 751.3
Sample B Female 547.2
Sample C Male 425.8
Sample D Male 367.6
Periaqueductal gray
nTPM: 423.6
Samples: 3

Max nTPM: 437.5
Min nTPM: 400.9
Sample B Female 437.5
Sample C Male 432.5
Sample D Male 400.9
Superior colliculi
nTPM: 555.7
Samples: 4

Max nTPM: 635.7
Min nTPM: 464.9
Sample A Female 635.7
Sample B Female 618.8
Sample C Male 503.5
Sample D Male 464.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

471.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 471.2
Samples: 4

Max nTPM: 506.3
Min nTPM: 420.7
Sample A Male 506.3
Sample B Male 461.4
Sample C Female 420.7
Sample D Female 496.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.0
68076526 Antisense, RP_040923_02_D09, Mouse strain C57BL/6J (56 days, male) 8.0

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