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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:415.1 nTPM
HPA Brain:511.6 nTPM
GTEx:415.1 nTPM
FANTOM5:32.9 Scaled Tags Per Million
Pig:56.9 nTPM
Mouse:107.5 nTPM
Allen mouse:5.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

511.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 279.2
1827 Male, age 72, unknown 397.8
2219 Male, age 76, both hemispheres 369.6
2411 Female, age 72, unknown 309.9
2019 Male, age 18, unknown 299.9
2666 Male, age 74, left hemisphere 290.8
2828 Female, age 72, unknown 270.5
1833 Male, age 53, unknown 232.8
1870 Female, age 42, unknown 230.3
1830 Male, age 51, unknown 206.9
2586 Male, age 75, left hemisphere 183.7
Dorsal raphe nucleus
nTPM: 322.3
2298 Female, age 72, unknown 403.6
2750 Male, age 76, both hemispheres 392.1
2047 Male, age 72, unknown 335.6
1828 Male, age 53, unknown 321.0
2016 Female, age 72, unknown 159.3
Inferior colliculus
nTPM: 229.0
2097 Female, age 72, unknown 239.2
1848 Female, age 42, unknown 231.2
2849 Male, age 72, unknown 230.9
1890 Male, age 53, unknown 214.9
Median raphe nucleus
nTPM: 511.6
2220 Male, age 76, midline 511.6
Periaquaductal grey, anterior
nTPM: 244.7
1795 Male, age 51, unknown 313.2
1947 Male, age 18, unknown 233.8
2502 Female, age 75, unknown 187.0
Periaquaductal grey, dorsal
nTPM: 217.3
2850 Male, age 76, both hemispheres 246.4
1831 Male, age 72, unknown 221.5
2464 Female, age 72, unknown 201.6
1840 Male, age 53, unknown 199.7
Periaquaductal grey, lateral
nTPM: 170.5
2140 Male, age 76, both hemispheres 183.2
2053 Male, age 18, unknown 165.0
2272 Male, age 74, both hemispheres 163.2
Pretectal area
nTPM: 335.5
1817 Female, age 42, unknown 518.5
1944 Female, age 72, unknown 489.8
2007 Male, age 72, unknown 464.1
1816 Male, age 51, unknown 453.1
2667 Female, age 75, unknown 421.0
1815 Male, age 53, unknown 382.5
2224 Female, age 72, unknown 314.6
2825 Male, age 18, unknown 226.7
2316 Male, age 76, right hemisphere 174.2
2407 Male, age 75, both hemispheres 127.5
2273 Male, age 74, both hemispheres 118.8
Red nucleus
nTPM: 215.1
2725 Female, age 75, unknown 333.1
2785 Male, age 18, unknown 291.2
1821 Female, age 72, unknown 250.9
2823 Male, age 76, right hemisphere 229.5
1954 Female, age 42, unknown 208.0
2584 Male, age 75, left hemisphere 202.0
2227 Male, age 72, unknown 191.2
2588 Male, age 74, left hemisphere 190.4
2769 Male, age 72, unknown 188.7
1865 Male, age 51, unknown 166.1
2503 Female, age 72, unknown 166.1
1904 Male, age 53, unknown 164.2
Substantia nigra
nTPM: 338.2
2665 Male, age 74, both hemispheres 635.2
1916 Female, age 42, unknown 463.4
1889 Female, age 72, unknown 447.8
1941 Male, age 53, unknown 413.0
1851 Male, age 51, unknown 331.9
2699 Male, age 18, unknown 265.0
2409 Female, age 72, unknown 256.4
2241 Male, age 72, unknown 228.7
2590 Female, age 75, unknown 204.3
2583 Male, age 75, right hemisphere 135.8
Superior colliculus
nTPM: 238.9
1895 Male, age 76, right hemisphere 351.6
2087 Female, age 72, unknown 346.6
1796 Male, age 53, unknown 294.5
2261 Male, age 18, unknown 242.4
2587 Male, age 74, left hemisphere 220.5
1839 Male, age 51, unknown 216.9
1913 Female, age 42, unknown 211.3
2668 Female, age 75, unknown 197.7
2664 Male, age 75, both hemispheres 161.0
1995 Male, age 72, unknown 146.6
Ventral tegmental area
nTPM: 315.4
2218 Male, age 76, both hemispheres 530.2
1915 Female, age 42, unknown 377.4
2410 Female, age 72, unknown 331.3
1942 Male, age 51, unknown 242.7
2021 Male, age 53, unknown 221.2
2223 Female, age 72, unknown 189.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

415.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 415.1
Samples: 139

Max nTPM: 1710.6
Min nTPM: 28.9
Std nTPM: 322.2
Median nTPM: 332.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1710.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1205.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1179.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1138.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1060.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1058.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 977.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 965.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 940.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 931.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 929.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 911.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 888.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 871.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 861.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 861.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 826.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 818.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 807.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 804.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 802.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 778.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 768.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 762.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 737.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 723.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 716.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 696.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 696.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 694.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 693.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 683.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 668.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 659.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 658.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 642.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 641.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 639.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 635.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 633.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 622.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 622.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 582.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 580.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 575.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 566.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 506.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 492.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 466.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 460.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 459.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 458.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 454.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 442.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 436.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 434.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 427.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 420.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 410.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 397.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 387.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 374.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 369.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 369.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 366.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 358.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 353.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 339.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 335.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 332.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 327.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 321.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 319.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 306.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 288.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 281.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 277.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 271.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 269.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 269.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 262.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 256.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 245.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 242.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 228.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 210.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 203.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 202.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 196.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 195.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 189.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 186.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 185.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 182.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 180.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 175.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 172.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 168.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 162.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 158.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 154.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 152.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 151.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 150.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 147.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 144.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 142.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 128.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 128.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 122.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 121.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 117.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 112.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 111.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 108.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 105.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 103.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 96.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 90.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 89.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 88.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 88.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 86.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 79.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 78.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 77.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 72.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 68.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 68.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 67.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 61.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 56.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 53.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 50.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 46.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 45.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 44.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 30.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 28.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

32.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 32.9
FF:10158-103A5 76 years, female 32.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

56.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 56.9
Samples: 4

Max nTPM: 100.4
Min nTPM: 7.6
Sample A Female 100.4
Sample B Female 37.9
Sample C Male 81.7
Sample D Male 7.6
Midbrain
nTPM: 19.8
Samples: 4

Max nTPM: 37.6
Min nTPM: 4.2
Sample A Female 4.2
Sample B Female 37.6
Sample C Male 6.3
Sample D Male 30.9
Periaqueductal gray
nTPM: 28.1
Samples: 3

Max nTPM: 45.9
Min nTPM: 16.5
Sample B Female 16.5
Sample C Male 45.9
Sample D Male 21.9
Superior colliculi
nTPM: 14.6
Samples: 4

Max nTPM: 29.7
Min nTPM: 3.0
Sample A Female 29.7
Sample B Female 3.0
Sample C Male 3.8
Sample D Male 21.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 107.5
Samples: 4

Max nTPM: 119.1
Min nTPM: 93.2
Sample A Male 109.3
Sample B Male 108.3
Sample C Female 93.2
Sample D Female 119.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.5
68545693 Antisense, RP_050120_01_D05, Mouse strain C57BL/6J (56 days, male) 5.9
72081426 Antisense, RP_051017_01_C05, Mouse strain C57BL/6J (56 days, male) 5.2

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