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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:540.5 nTPM
HPA Brain:1287.6 nTPM
GTEx:540.5 nTPM
FANTOM5:1488.1 Scaled Tags Per Million
Pig:859.4 nTPM
Mouse:338.5 nTPM
Allen mouse:14.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1287.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 998.1
2411 Female, age 72, unknown 1386.2
1830 Male, age 51, unknown 1223.2
1870 Female, age 42, unknown 1197.6
1833 Male, age 53, unknown 1167.3
2019 Male, age 18, unknown 1150.8
2828 Female, age 72, unknown 991.0
2586 Male, age 75, left hemisphere 746.4
2666 Male, age 74, left hemisphere 733.5
1827 Male, age 72, unknown 725.7
2219 Male, age 76, both hemispheres 659.2
Dorsal raphe nucleus
nTPM: 718.9
2750 Male, age 76, both hemispheres 1303.3
2016 Female, age 72, unknown 795.7
1828 Male, age 53, unknown 649.8
2298 Female, age 72, unknown 459.5
2047 Male, age 72, unknown 386.4
Inferior colliculus
nTPM: 621.7
1890 Male, age 53, unknown 656.0
1848 Female, age 42, unknown 645.5
2849 Male, age 72, unknown 599.9
2097 Female, age 72, unknown 585.1
Median raphe nucleus
nTPM: 506.5
2220 Male, age 76, midline 506.5
Periaquaductal grey, anterior
nTPM: 561.3
2502 Female, age 75, unknown 639.5
1947 Male, age 18, unknown 580.7
1795 Male, age 51, unknown 463.9
Periaquaductal grey, dorsal
nTPM: 455.5
2464 Female, age 72, unknown 763.0
1831 Male, age 72, unknown 481.8
1840 Male, age 53, unknown 303.1
2850 Male, age 76, both hemispheres 274.1
Periaquaductal grey, lateral
nTPM: 501.6
2272 Male, age 74, both hemispheres 601.8
2053 Male, age 18, unknown 585.5
2140 Male, age 76, both hemispheres 317.4
Pretectal area
nTPM: 637.3
2316 Male, age 76, right hemisphere 956.0
1815 Male, age 53, unknown 906.6
2407 Male, age 75, both hemispheres 880.7
1817 Female, age 42, unknown 664.2
2007 Male, age 72, unknown 658.2
2825 Male, age 18, unknown 638.3
2273 Male, age 74, both hemispheres 569.3
2667 Female, age 75, unknown 512.6
2224 Female, age 72, unknown 493.5
1816 Male, age 51, unknown 366.0
1944 Female, age 72, unknown 365.2
Red nucleus
nTPM: 1287.6
1865 Male, age 51, unknown 1547.5
1904 Male, age 53, unknown 1535.5
1821 Female, age 72, unknown 1457.8
2823 Male, age 76, right hemisphere 1439.6
2769 Male, age 72, unknown 1432.4
2227 Male, age 72, unknown 1414.9
2785 Male, age 18, unknown 1329.6
2503 Female, age 72, unknown 1263.4
1954 Female, age 42, unknown 1188.7
2588 Male, age 74, left hemisphere 1104.6
2725 Female, age 75, unknown 869.5
2584 Male, age 75, left hemisphere 867.6
Substantia nigra
nTPM: 711.0
1851 Male, age 51, unknown 928.9
2590 Female, age 75, unknown 889.3
2583 Male, age 75, right hemisphere 882.9
2409 Female, age 72, unknown 854.0
1889 Female, age 72, unknown 740.0
2699 Male, age 18, unknown 664.8
2241 Male, age 72, unknown 598.6
1941 Male, age 53, unknown 554.4
1916 Female, age 42, unknown 538.1
2665 Male, age 74, both hemispheres 458.8
Superior colliculus
nTPM: 860.1
1995 Male, age 72, unknown 1383.4
1913 Female, age 42, unknown 1263.5
1895 Male, age 76, right hemisphere 1022.9
2668 Female, age 75, unknown 947.4
1839 Male, age 51, unknown 854.9
2587 Male, age 74, left hemisphere 850.0
1796 Male, age 53, unknown 688.3
2664 Male, age 75, both hemispheres 587.6
2261 Male, age 18, unknown 506.2
2087 Female, age 72, unknown 497.2
Ventral tegmental area
nTPM: 809.9
2223 Female, age 72, unknown 1051.9
2410 Female, age 72, unknown 1049.6
1942 Male, age 51, unknown 719.9
1915 Female, age 42, unknown 710.9
2021 Male, age 53, unknown 699.8
2218 Male, age 76, both hemispheres 627.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

540.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 540.5
Samples: 139

Max nTPM: 2222.5
Min nTPM: 152.6
Std nTPM: 331.8
Median nTPM: 447.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2222.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2072.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1676.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1419.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1174.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1162.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1160.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1148.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1085.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1084.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1073.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1018.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 977.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 967.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 961.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 955.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 929.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 910.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 848.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 794.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 772.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 768.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 760.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 748.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 724.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 714.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 711.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 698.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 693.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 687.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 685.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 680.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 676.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 673.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 665.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 626.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 624.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 614.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 611.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 590.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 577.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 577.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 574.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 574.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 572.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 570.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 568.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 568.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 560.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 557.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 546.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 528.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 510.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 498.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 496.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 495.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 493.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 490.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 486.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 486.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 484.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 476.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 470.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 465.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 463.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 458.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 457.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 452.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 450.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 447.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 446.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 442.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 441.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 440.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 439.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 437.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 429.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 428.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 426.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 426.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 423.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 420.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 416.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 414.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 413.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 408.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 398.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 398.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 391.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 390.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 386.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 382.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 377.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 373.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 371.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 371.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 369.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 366.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 362.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 354.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 349.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 327.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 322.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 317.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 314.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 308.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 305.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 300.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 299.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 297.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 296.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 296.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 295.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 294.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 289.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 282.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 282.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 281.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 281.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 280.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 269.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 265.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 265.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 264.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 255.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 253.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 251.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 250.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 241.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 217.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 210.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 203.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 201.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 199.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 195.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 189.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 165.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 165.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 152.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1488.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1488.1
FF:10158-103A5 76 years, female 1488.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

859.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 768.7
Samples: 4

Max nTPM: 1262.5
Min nTPM: 453.6
Sample A Female 790.3
Sample B Female 453.6
Sample C Male 568.5
Sample D Male 1262.5
Midbrain
nTPM: 859.4
Samples: 4

Max nTPM: 1887.9
Min nTPM: 357.9
Sample A Female 1887.9
Sample B Female 787.5
Sample C Male 357.9
Sample D Male 404.2
Periaqueductal gray
nTPM: 511.0
Samples: 3

Max nTPM: 632.0
Min nTPM: 367.8
Sample B Female 632.0
Sample C Male 367.8
Sample D Male 533.1
Superior colliculi
nTPM: 632.7
Samples: 4

Max nTPM: 785.0
Min nTPM: 338.5
Sample A Female 780.5
Sample B Female 338.5
Sample C Male 626.6
Sample D Male 785.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

338.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 338.6
Samples: 4

Max nTPM: 362.7
Min nTPM: 298.1
Sample A Male 362.7
Sample B Male 298.1
Sample C Female 330.7
Sample D Female 362.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.8
77371841 Antisense, RP_070129_01_A04, Mouse strain C57BL/6J (56 days, male) 17.5
79488913 Antisense, RP_070129_01_A04, Mouse strain C57BL/6J (56 days, male) 14.8
1175 Antisense, RP_040407_02_H04, Mouse strain C57BL/6J (56 days, male) 12.2
1176 Antisense, RP_040407_02_H04, Mouse strain C57BL/6J (56 days, male) 10.4

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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