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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1271.7 nTPM
HPA Brain:1993.1 nTPM
GTEx:1271.7 nTPM
FANTOM5:2232.8 Scaled Tags Per Million
Pig:2633.2 nTPM
Mouse:591.4 nTPM
Allen mouse:23.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1993.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1741.5
2019 Male, age 18, unknown 1985.1
1870 Female, age 42, unknown 1962.9
1830 Male, age 51, unknown 1879.6
2411 Female, age 72, unknown 1873.3
1833 Male, age 53, unknown 1824.2
2828 Female, age 72, unknown 1769.7
2666 Male, age 74, left hemisphere 1756.1
1827 Male, age 72, unknown 1572.5
2586 Male, age 75, left hemisphere 1530.5
2219 Male, age 76, both hemispheres 1260.9
Dorsal raphe nucleus
nTPM: 1656.8
2750 Male, age 76, both hemispheres 1957.2
2298 Female, age 72, unknown 1719.9
1828 Male, age 53, unknown 1627.8
2016 Female, age 72, unknown 1499.4
2047 Male, age 72, unknown 1479.8
Inferior colliculus
nTPM: 1517.3
1848 Female, age 42, unknown 1582.3
2097 Female, age 72, unknown 1533.9
1890 Male, age 53, unknown 1489.3
2849 Male, age 72, unknown 1463.6
Median raphe nucleus
nTPM: 1792.2
2220 Male, age 76, midline 1792.2
Periaquaductal grey, anterior
nTPM: 1565.6
1947 Male, age 18, unknown 1637.9
1795 Male, age 51, unknown 1619.8
2502 Female, age 75, unknown 1439.1
Periaquaductal grey, dorsal
nTPM: 1431.8
2850 Male, age 76, both hemispheres 1614.9
1831 Male, age 72, unknown 1501.6
2464 Female, age 72, unknown 1373.8
1840 Male, age 53, unknown 1237.0
Periaquaductal grey, lateral
nTPM: 1598.9
2272 Male, age 74, both hemispheres 1846.4
2140 Male, age 76, both hemispheres 1496.3
2053 Male, age 18, unknown 1454.0
Pretectal area
nTPM: 1711.3
1817 Female, age 42, unknown 2036.3
2007 Male, age 72, unknown 1851.1
1815 Male, age 53, unknown 1829.9
2273 Male, age 74, both hemispheres 1797.1
1944 Female, age 72, unknown 1782.8
1816 Male, age 51, unknown 1667.7
2667 Female, age 75, unknown 1642.3
2407 Male, age 75, both hemispheres 1628.5
2224 Female, age 72, unknown 1595.2
2316 Male, age 76, right hemisphere 1516.5
2825 Male, age 18, unknown 1477.1
Red nucleus
nTPM: 1993.1
1865 Male, age 51, unknown 2212.3
1904 Male, age 53, unknown 2156.1
2769 Male, age 72, unknown 2143.7
2227 Male, age 72, unknown 2127.0
2785 Male, age 18, unknown 2123.0
1821 Female, age 72, unknown 2080.1
2725 Female, age 75, unknown 2069.7
1954 Female, age 42, unknown 2044.5
2503 Female, age 72, unknown 1969.5
2823 Male, age 76, right hemisphere 1894.3
2584 Male, age 75, left hemisphere 1707.2
2588 Male, age 74, left hemisphere 1390.2
Substantia nigra
nTPM: 1759.9
2583 Male, age 75, right hemisphere 2142.2
2590 Female, age 75, unknown 2063.9
1916 Female, age 42, unknown 1815.6
1851 Male, age 51, unknown 1772.7
1941 Male, age 53, unknown 1765.1
1889 Female, age 72, unknown 1748.4
2665 Male, age 74, both hemispheres 1689.6
2699 Male, age 18, unknown 1618.1
2409 Female, age 72, unknown 1571.0
2241 Male, age 72, unknown 1412.5
Superior colliculus
nTPM: 1678.7
1913 Female, age 42, unknown 2062.5
1995 Male, age 72, unknown 1951.7
2587 Male, age 74, left hemisphere 1948.0
1796 Male, age 53, unknown 1751.0
2261 Male, age 18, unknown 1749.2
2087 Female, age 72, unknown 1653.6
1839 Male, age 51, unknown 1565.8
2668 Female, age 75, unknown 1513.9
1895 Male, age 76, right hemisphere 1298.7
2664 Male, age 75, both hemispheres 1292.7
Ventral tegmental area
nTPM: 1835.2
2223 Female, age 72, unknown 2361.2
2218 Male, age 76, both hemispheres 1898.1
2410 Female, age 72, unknown 1885.6
1915 Female, age 42, unknown 1689.7
2021 Male, age 53, unknown 1638.3
1942 Male, age 51, unknown 1538.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1271.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1271.7
Samples: 139

Max nTPM: 3111.1
Min nTPM: 628.5
Std nTPM: 476.6
Median nTPM: 1106.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 3111.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 2922.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2824.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2799.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 2744.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2634.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 2608.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 2455.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 2265.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2215.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 2102.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 2036.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1917.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1883.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1806.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1767.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1683.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1662.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1634.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1634.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1622.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1620.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1575.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1572.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1557.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1527.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1526.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1517.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1502.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1458.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1424.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1423.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 1417.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1415.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1381.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1381.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1378.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1345.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1341.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1333.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1333.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1328.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1326.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1324.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1316.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1293.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1285.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1284.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1276.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1269.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1248.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1245.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1231.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1199.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1180.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1176.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1160.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1152.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1147.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1145.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1142.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1139.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1128.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1115.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1115.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1114.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1110.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1108.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1106.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1106.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1102.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1098.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1098.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1096.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1094.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1087.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1075.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1074.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1070.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1069.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1066.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1063.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1062.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1057.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1057.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1055.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1049.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1042.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1036.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1035.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1034.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1032.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1031.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1031.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1017.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1016.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1014.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1009.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1001.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 993.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 991.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 989.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 989.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 986.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 982.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 978.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 968.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 967.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 966.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 959.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 958.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 957.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 951.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 949.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 946.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 946.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 938.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 936.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 933.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 933.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 931.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 915.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 913.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 904.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 896.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 895.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 879.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 878.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 862.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 845.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 835.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 826.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 821.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 818.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 780.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 744.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 725.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 702.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 628.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

2232.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2232.8
FF:10158-103A5 76 years, female 2232.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2633.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 2528.8
Samples: 4

Max nTPM: 2800.0
Min nTPM: 2229.5
Sample A Female 2800.0
Sample B Female 2229.5
Sample C Male 2539.8
Sample D Male 2546.0
Midbrain
nTPM: 2633.2
Samples: 4

Max nTPM: 4445.4
Min nTPM: 1725.7
Sample A Female 4445.4
Sample B Female 2315.1
Sample C Male 2046.5
Sample D Male 1725.7
Periaqueductal gray
nTPM: 1985.3
Samples: 3

Max nTPM: 2263.5
Min nTPM: 1700.5
Sample B Female 1992.0
Sample C Male 2263.5
Sample D Male 1700.5
Superior colliculi
nTPM: 2379.4
Samples: 4

Max nTPM: 2761.2
Min nTPM: 2077.8
Sample A Female 2761.2
Sample B Female 2077.8
Sample C Male 2346.4
Sample D Male 2332.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

591.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 591.4
Samples: 4

Max nTPM: 651.7
Min nTPM: 554.3
Sample A Male 651.7
Sample B Male 564.0
Sample C Female 554.3
Sample D Female 595.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

23.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 23.3
74881516 Antisense, RP_060315_04_C04, Mouse strain C57BL/6J (56 days, male) 25.3
81600126 Antisense, RP_080306_03_B07, Mouse strain C57BL/6J (56 days, male) 25.2
69514684 Antisense, RP_050419_03_H03, Mouse strain C57BL/6J (56 days, male) 19.4

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