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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:422.0 nTPM
HPA Brain:1941.4 nTPM
GTEx:422.0 nTPM
FANTOM5:557.8 Scaled Tags Per Million
Pig:1549.8 nTPM
Mouse:2313.8 nTPM
Allen mouse:5.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1941.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 986.8
2411 Female, age 72, unknown 1224.0
1870 Female, age 42, unknown 1143.9
1827 Male, age 72, unknown 1137.0
2219 Male, age 76, both hemispheres 1091.9
1833 Male, age 53, unknown 1009.0
2586 Male, age 75, left hemisphere 965.4
2666 Male, age 74, left hemisphere 916.2
1830 Male, age 51, unknown 870.1
2019 Male, age 18, unknown 786.2
2828 Female, age 72, unknown 724.4
Dorsal raphe nucleus
nTPM: 1410.6
2047 Male, age 72, unknown 1891.5
2298 Female, age 72, unknown 1805.2
2750 Male, age 76, both hemispheres 1298.5
1828 Male, age 53, unknown 1133.4
2016 Female, age 72, unknown 924.1
Inferior colliculus
nTPM: 1269.9
1848 Female, age 42, unknown 1448.8
2097 Female, age 72, unknown 1282.0
2849 Male, age 72, unknown 1276.9
1890 Male, age 53, unknown 1072.0
Median raphe nucleus
nTPM: 1941.4
2220 Male, age 76, midline 1941.4
Periaquaductal grey, anterior
nTPM: 1046.2
1795 Male, age 51, unknown 1118.6
2502 Female, age 75, unknown 1014.9
1947 Male, age 18, unknown 1005.1
Periaquaductal grey, dorsal
nTPM: 1090.2
1840 Male, age 53, unknown 1408.8
2850 Male, age 76, both hemispheres 1147.1
2464 Female, age 72, unknown 985.3
1831 Male, age 72, unknown 819.8
Periaquaductal grey, lateral
nTPM: 959.1
2053 Male, age 18, unknown 976.4
2272 Male, age 74, both hemispheres 972.7
2140 Male, age 76, both hemispheres 928.2
Pretectal area
nTPM: 996.7
2224 Female, age 72, unknown 1340.5
1944 Female, age 72, unknown 1183.6
2007 Male, age 72, unknown 1127.5
2825 Male, age 18, unknown 1075.2
1817 Female, age 42, unknown 993.5
1816 Male, age 51, unknown 982.8
2667 Female, age 75, unknown 945.2
2316 Male, age 76, right hemisphere 907.5
2273 Male, age 74, both hemispheres 896.2
1815 Male, age 53, unknown 824.4
2407 Male, age 75, both hemispheres 687.5
Red nucleus
nTPM: 769.2
1821 Female, age 72, unknown 969.7
2785 Male, age 18, unknown 835.6
2769 Male, age 72, unknown 809.6
2227 Male, age 72, unknown 799.8
1954 Female, age 42, unknown 785.1
2503 Female, age 72, unknown 779.6
2725 Female, age 75, unknown 772.8
2584 Male, age 75, left hemisphere 750.1
2588 Male, age 74, left hemisphere 745.5
1904 Male, age 53, unknown 695.6
1865 Male, age 51, unknown 687.1
2823 Male, age 76, right hemisphere 600.4
Substantia nigra
nTPM: 1020.9
1916 Female, age 42, unknown 1205.0
1889 Female, age 72, unknown 1204.3
1941 Male, age 53, unknown 1186.1
2665 Male, age 74, both hemispheres 1076.0
2241 Male, age 72, unknown 1017.7
1851 Male, age 51, unknown 1017.5
2699 Male, age 18, unknown 1008.4
2590 Female, age 75, unknown 911.0
2409 Female, age 72, unknown 796.5
2583 Male, age 75, right hemisphere 786.4
Superior colliculus
nTPM: 911.8
1895 Male, age 76, right hemisphere 1154.3
1839 Male, age 51, unknown 1098.7
1796 Male, age 53, unknown 1076.0
2668 Female, age 75, unknown 1040.6
2261 Male, age 18, unknown 939.2
2087 Female, age 72, unknown 932.4
2587 Male, age 74, left hemisphere 903.9
2664 Male, age 75, both hemispheres 842.0
1913 Female, age 42, unknown 581.4
1995 Male, age 72, unknown 549.2
Ventral tegmental area
nTPM: 1081.2
2410 Female, age 72, unknown 1227.8
1915 Female, age 42, unknown 1202.4
2218 Male, age 76, both hemispheres 1089.8
2021 Male, age 53, unknown 1023.6
1942 Male, age 51, unknown 1002.6
2223 Female, age 72, unknown 941.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

422.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 422.0
Samples: 139

Max nTPM: 1617.6
Min nTPM: 159.7
Std nTPM: 207.1
Median nTPM: 355.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1617.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1313.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 945.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 894.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 860.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 842.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 830.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 825.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 781.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 744.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 736.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 701.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 699.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 692.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 692.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 672.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 659.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 653.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 644.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 644.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 643.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 563.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 563.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 562.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 555.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 547.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 544.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 525.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 522.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 515.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 510.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 503.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 498.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 497.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 493.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 488.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 486.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 477.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 460.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 458.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 456.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 445.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 429.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 426.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 426.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 423.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 421.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 419.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 417.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 414.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 408.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 402.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 399.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 397.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 397.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 396.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 396.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 390.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 385.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 381.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 376.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 374.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 372.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 372.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 369.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 369.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 365.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 362.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 356.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 355.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 354.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 352.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 351.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 347.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 346.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 342.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 340.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 338.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 337.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 334.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 333.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 333.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 332.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 330.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 330.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 328.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 327.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 327.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 324.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 324.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 322.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 317.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 317.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 314.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 311.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 310.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 308.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 305.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 302.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 300.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 294.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 294.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 292.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 292.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 290.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 289.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 289.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 288.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 288.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 285.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 283.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 277.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 275.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 274.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 270.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 269.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 266.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 264.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 261.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 261.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 260.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 260.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 260.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 257.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 255.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 253.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 248.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 245.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 244.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 241.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 236.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 234.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 225.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 225.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 220.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 208.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 196.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 183.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 159.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

557.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 557.8
FF:10158-103A5 76 years, female 557.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1549.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 1456.9
Samples: 4

Max nTPM: 1828.5
Min nTPM: 1106.8
Sample A Female 1688.6
Sample B Female 1203.7
Sample C Male 1828.5
Sample D Male 1106.8
Midbrain
nTPM: 1532.5
Samples: 4

Max nTPM: 1770.7
Min nTPM: 1341.7
Sample A Female 1455.0
Sample B Female 1341.7
Sample C Male 1562.4
Sample D Male 1770.7
Periaqueductal gray
nTPM: 1549.8
Samples: 3

Max nTPM: 2071.4
Min nTPM: 1250.5
Sample B Female 1327.5
Sample C Male 2071.4
Sample D Male 1250.5
Superior colliculi
nTPM: 1514.4
Samples: 4

Max nTPM: 1804.2
Min nTPM: 1182.6
Sample A Female 1635.7
Sample B Female 1182.6
Sample C Male 1804.2
Sample D Male 1434.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2313.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 2313.8
Samples: 4

Max nTPM: 2364.6
Min nTPM: 2255.0
Sample A Male 2255.0
Sample B Male 2364.6
Sample C Female 2281.6
Sample D Female 2353.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.8
509 Antisense, RP_040507_01_H03, Mouse strain C57BL/6J (56 days, male) 17.3
510 Antisense, RP_040507_01_H03, Mouse strain C57BL/6J (56 days, male) 12.7
511 Sense, RPS_Baylor_36998, Mouse strain C57BL/6J (56 days, male) 0.0
70230813 Antisense, RP_050524_04_E07, Mouse strain C57BL/6J (56 days, male) 0.0

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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