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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:192.2 nTPM
HPA Brain:342.9 nTPM
GTEx:192.2 nTPM
FANTOM5:87.8 Scaled Tags Per Million
Pig:488.1 nTPM
Mouse:719.3 nTPM
Allen mouse:24.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

342.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 295.5
2019 Male, age 18, unknown 388.8
1827 Male, age 72, unknown 362.2
2666 Male, age 74, left hemisphere 346.6
2411 Female, age 72, unknown 334.8
2219 Male, age 76, both hemispheres 329.3
2586 Male, age 75, left hemisphere 270.2
2828 Female, age 72, unknown 260.4
1870 Female, age 42, unknown 237.0
1833 Male, age 53, unknown 222.0
1830 Male, age 51, unknown 204.3
Dorsal raphe nucleus
nTPM: 297.4
2298 Female, age 72, unknown 408.1
2047 Male, age 72, unknown 325.3
1828 Male, age 53, unknown 316.8
2750 Male, age 76, both hemispheres 267.2
2016 Female, age 72, unknown 169.8
Inferior colliculus
nTPM: 286.2
2097 Female, age 72, unknown 352.0
1848 Female, age 42, unknown 286.4
1890 Male, age 53, unknown 279.6
2849 Male, age 72, unknown 226.9
Median raphe nucleus
nTPM: 331.5
2220 Male, age 76, midline 331.5
Periaquaductal grey, anterior
nTPM: 302.6
1795 Male, age 51, unknown 327.7
1947 Male, age 18, unknown 302.6
2502 Female, age 75, unknown 277.5
Periaquaductal grey, dorsal
nTPM: 228.2
1831 Male, age 72, unknown 250.2
1840 Male, age 53, unknown 243.2
2464 Female, age 72, unknown 228.6
2850 Male, age 76, both hemispheres 190.9
Periaquaductal grey, lateral
nTPM: 212.3
2272 Male, age 74, both hemispheres 243.0
2053 Male, age 18, unknown 206.0
2140 Male, age 76, both hemispheres 187.8
Pretectal area
nTPM: 342.9
1944 Female, age 72, unknown 499.9
1816 Male, age 51, unknown 489.3
2007 Male, age 72, unknown 485.3
1817 Female, age 42, unknown 451.0
1815 Male, age 53, unknown 344.4
2667 Female, age 75, unknown 325.2
2224 Female, age 72, unknown 299.8
2407 Male, age 75, both hemispheres 228.6
2273 Male, age 74, both hemispheres 217.9
2316 Male, age 76, right hemisphere 216.2
2825 Male, age 18, unknown 214.7
Red nucleus
nTPM: 237.4
2785 Male, age 18, unknown 340.4
1821 Female, age 72, unknown 282.5
2584 Male, age 75, left hemisphere 274.1
2725 Female, age 75, unknown 249.4
1954 Female, age 42, unknown 240.4
2588 Male, age 74, left hemisphere 235.7
2823 Male, age 76, right hemisphere 225.4
1865 Male, age 51, unknown 203.3
1904 Male, age 53, unknown 202.6
2227 Male, age 72, unknown 201.2
2503 Female, age 72, unknown 199.8
2769 Male, age 72, unknown 194.1
Substantia nigra
nTPM: 322.5
1941 Male, age 53, unknown 447.9
1916 Female, age 42, unknown 440.3
1889 Female, age 72, unknown 419.1
1851 Male, age 51, unknown 357.0
2241 Male, age 72, unknown 332.8
2409 Female, age 72, unknown 282.9
2665 Male, age 74, both hemispheres 282.6
2590 Female, age 75, unknown 225.7
2583 Male, age 75, right hemisphere 223.5
2699 Male, age 18, unknown 213.3
Superior colliculus
nTPM: 283.1
2087 Female, age 72, unknown 409.1
2668 Female, age 75, unknown 384.7
1796 Male, age 53, unknown 317.0
2261 Male, age 18, unknown 315.5
1895 Male, age 76, right hemisphere 306.2
1839 Male, age 51, unknown 247.0
2664 Male, age 75, both hemispheres 231.1
1913 Female, age 42, unknown 218.9
2587 Male, age 74, left hemisphere 210.9
1995 Male, age 72, unknown 190.4
Ventral tegmental area
nTPM: 309.3
2218 Male, age 76, both hemispheres 391.5
2410 Female, age 72, unknown 372.8
1915 Female, age 42, unknown 339.8
1942 Male, age 51, unknown 290.7
2223 Female, age 72, unknown 241.8
2021 Male, age 53, unknown 219.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

192.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 192.2
Samples: 139

Max nTPM: 918.8
Min nTPM: 55.5
Std nTPM: 135.5
Median nTPM: 142.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 918.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 714.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 550.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 523.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 477.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 472.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 448.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 433.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 432.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 430.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 414.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 407.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 400.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 382.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 358.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 357.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 349.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 349.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 337.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 326.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 308.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 299.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 298.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 297.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 295.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 292.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 287.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 273.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 270.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 268.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 259.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 256.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 256.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 253.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 247.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 244.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 241.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 239.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 228.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 225.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 221.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 220.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 219.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 216.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 215.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 214.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 213.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 208.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 203.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 203.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 199.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 199.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 196.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 190.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 189.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 184.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 179.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 176.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 174.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 170.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 170.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 168.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 167.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 160.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 156.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 152.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 148.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 148.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 148.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 142.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 140.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 138.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 136.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 134.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 133.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 132.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 132.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 131.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 127.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 126.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 125.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 120.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 118.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 118.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 118.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 117.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 116.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 114.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 111.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 110.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 110.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 107.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 106.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 104.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 104.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 104.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 103.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 102.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 101.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 100.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 100.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 99.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 99.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 98.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 96.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 95.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 93.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 93.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 93.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 92.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 91.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 91.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 88.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 88.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 87.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 87.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 86.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 85.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 85.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 83.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 82.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 81.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 79.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 79.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 76.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 76.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 75.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 72.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 70.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 70.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 68.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 67.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 67.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 66.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 64.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 63.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 62.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 61.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 55.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

87.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 87.8
FF:10158-103A5 76 years, female 87.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

488.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 283.0
Samples: 4

Max nTPM: 448.5
Min nTPM: 86.2
Sample A Female 448.5
Sample B Female 204.8
Sample C Male 392.6
Sample D Male 86.2
Midbrain
nTPM: 398.7
Samples: 4

Max nTPM: 720.6
Min nTPM: 123.1
Sample A Female 123.1
Sample B Female 236.3
Sample C Male 720.6
Sample D Male 514.7
Periaqueductal gray
nTPM: 266.5
Samples: 3

Max nTPM: 344.4
Min nTPM: 218.6
Sample B Female 236.6
Sample C Male 344.4
Sample D Male 218.6
Superior colliculi
nTPM: 488.2
Samples: 4

Max nTPM: 698.1
Min nTPM: 311.5
Sample A Female 509.7
Sample B Female 311.5
Sample C Male 698.1
Sample D Male 433.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

719.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 719.3
Samples: 4

Max nTPM: 725.1
Min nTPM: 710.1
Sample A Male 725.1
Sample B Male 710.1
Sample C Female 717.2
Sample D Female 724.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

24.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 24.8
112197625 Antisense, RP_110421_01_F07, Mouse strain C57BL/6J (56 days, male) 27.4
79360272 Antisense, RP_071018_01_G01, Mouse strain C57BL/6J (56 days, male) 22.1

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