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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:897.9 nTPM
HPA Brain:2636.8 nTPM
GTEx:897.9 nTPM
FANTOM5:2275.6 Scaled Tags Per Million
Pig:1523.7 nTPM
Mouse:1586.9 nTPM
Allen mouse:9.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2636.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1708.1
2828 Female, age 72, unknown 2644.4
1870 Female, age 42, unknown 2161.5
1827 Male, age 72, unknown 1891.3
2411 Female, age 72, unknown 1741.0
1833 Male, age 53, unknown 1708.7
2666 Male, age 74, left hemisphere 1700.3
1830 Male, age 51, unknown 1616.7
2586 Male, age 75, left hemisphere 1530.3
2219 Male, age 76, both hemispheres 1498.9
2019 Male, age 18, unknown 588.2
Dorsal raphe nucleus
nTPM: 2369.7
2016 Female, age 72, unknown 2880.2
2298 Female, age 72, unknown 2462.4
2047 Male, age 72, unknown 2437.7
1828 Male, age 53, unknown 2297.8
2750 Male, age 76, both hemispheres 1770.3
Inferior colliculus
nTPM: 1686.5
2849 Male, age 72, unknown 2320.2
2097 Female, age 72, unknown 1746.8
1890 Male, age 53, unknown 1654.5
1848 Female, age 42, unknown 1024.5
Median raphe nucleus
nTPM: 2145.3
2220 Male, age 76, midline 2145.3
Periaquaductal grey, anterior
nTPM: 2279.1
1795 Male, age 51, unknown 2704.5
1947 Male, age 18, unknown 2343.6
2502 Female, age 75, unknown 1789.2
Periaquaductal grey, dorsal
nTPM: 2203.7
1840 Male, age 53, unknown 2492.1
2850 Male, age 76, both hemispheres 2485.5
2464 Female, age 72, unknown 2255.1
1831 Male, age 72, unknown 1581.9
Periaquaductal grey, lateral
nTPM: 2636.8
2053 Male, age 18, unknown 3646.6
2140 Male, age 76, both hemispheres 2189.6
2272 Male, age 74, both hemispheres 2074.0
Pretectal area
nTPM: 1668.7
2825 Male, age 18, unknown 3340.3
2224 Female, age 72, unknown 2721.3
2407 Male, age 75, both hemispheres 2263.0
2667 Female, age 75, unknown 2195.7
2273 Male, age 74, both hemispheres 2112.3
2316 Male, age 76, right hemisphere 1264.8
1944 Female, age 72, unknown 1170.6
1815 Male, age 53, unknown 1024.8
1817 Female, age 42, unknown 835.3
1816 Male, age 51, unknown 786.0
2007 Male, age 72, unknown 641.7
Red nucleus
nTPM: 1815.7
2769 Male, age 72, unknown 2538.7
2227 Male, age 72, unknown 2487.8
2503 Female, age 72, unknown 2332.2
2725 Female, age 75, unknown 2066.7
1821 Female, age 72, unknown 1977.5
1865 Male, age 51, unknown 1971.4
1954 Female, age 42, unknown 1908.5
1904 Male, age 53, unknown 1628.0
2584 Male, age 75, left hemisphere 1580.4
2588 Male, age 74, left hemisphere 1381.3
2823 Male, age 76, right hemisphere 1326.8
2785 Male, age 18, unknown 588.9
Substantia nigra
nTPM: 2032.8
2699 Male, age 18, unknown 4091.3
1916 Female, age 42, unknown 2663.0
1851 Male, age 51, unknown 2289.4
2665 Male, age 74, both hemispheres 2164.2
2590 Female, age 75, unknown 1710.1
1941 Male, age 53, unknown 1681.5
2409 Female, age 72, unknown 1595.0
2583 Male, age 75, right hemisphere 1515.2
2241 Male, age 72, unknown 1403.9
1889 Female, age 72, unknown 1214.8
Superior colliculus
nTPM: 1313.4
1796 Male, age 53, unknown 1677.4
1913 Female, age 42, unknown 1586.7
2587 Male, age 74, left hemisphere 1482.1
1995 Male, age 72, unknown 1433.4
1839 Male, age 51, unknown 1396.5
2261 Male, age 18, unknown 1388.0
2664 Male, age 75, both hemispheres 1271.3
2087 Female, age 72, unknown 1144.5
2668 Female, age 75, unknown 985.0
1895 Male, age 76, right hemisphere 769.4
Ventral tegmental area
nTPM: 2117.4
1915 Female, age 42, unknown 2445.9
2021 Male, age 53, unknown 2234.6
1942 Male, age 51, unknown 2148.2
2218 Male, age 76, both hemispheres 1988.9
2410 Female, age 72, unknown 1980.8
2223 Female, age 72, unknown 1906.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

897.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 897.9
Samples: 139

Max nTPM: 2725.6
Min nTPM: 131.7
Std nTPM: 422.6
Median nTPM: 789.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 2725.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2332.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2179.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1995.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1929.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1737.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1667.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1659.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1627.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1602.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1594.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1566.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1522.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1490.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1453.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1432.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1414.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1412.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1304.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1286.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1279.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1273.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1261.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1242.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1221.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1191.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1191.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1182.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1179.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1165.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1160.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1151.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1137.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1132.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1120.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1119.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1098.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1026.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1023.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1022.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1018.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1018.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1011.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 988.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 976.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 973.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 970.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 964.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 951.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 947.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 943.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 933.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 929.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 905.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 905.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 903.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 898.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 894.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 885.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 865.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 858.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 858.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 845.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 841.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 820.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 816.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 805.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 800.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 791.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 789.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 785.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 781.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 767.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 766.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 763.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 761.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 754.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 751.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 745.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 742.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 739.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 738.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 738.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 731.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 720.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 719.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 709.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 707.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 706.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 692.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 682.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 669.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 667.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 664.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 648.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 647.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 637.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 631.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 622.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 622.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 618.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 615.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 612.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 593.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 589.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 587.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 584.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 584.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 582.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 575.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 575.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 569.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 551.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 550.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 542.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 537.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 532.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 529.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 523.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 515.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 507.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 503.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 490.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 483.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 482.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 479.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 467.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 457.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 442.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 436.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 418.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 415.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 411.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 394.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 394.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 359.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 322.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 298.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 131.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

2275.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2275.6
FF:10158-103A5 76 years, female 2275.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1523.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 1523.7
Samples: 4

Max nTPM: 1846.1
Min nTPM: 1324.4
Sample A Female 1324.4
Sample B Female 1508.5
Sample C Male 1415.9
Sample D Male 1846.1
Midbrain
nTPM: 926.9
Samples: 4

Max nTPM: 1242.9
Min nTPM: 770.2
Sample A Female 770.2
Sample B Female 1242.9
Sample C Male 858.0
Sample D Male 836.6
Periaqueductal gray
nTPM: 997.4
Samples: 3

Max nTPM: 1189.7
Min nTPM: 827.8
Sample B Female 974.6
Sample C Male 1189.7
Sample D Male 827.8
Superior colliculi
nTPM: 947.5
Samples: 4

Max nTPM: 1288.0
Min nTPM: 795.9
Sample A Female 1288.0
Sample B Female 795.9
Sample C Male 804.3
Sample D Male 901.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1586.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 1586.9
Samples: 4

Max nTPM: 1662.3
Min nTPM: 1488.7
Sample A Male 1662.3
Sample B Male 1488.7
Sample C Female 1546.2
Sample D Female 1650.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.3
73788443 Antisense, RP_051213_01_B02, Mouse strain C57BL/6J (56 days, male) 10.0
73512200 Antisense, RP_050712_04_F12, Mouse strain C57BL/6J (56 days, male) 8.9
70429441 Antisense, RP_050614_01_F09, Mouse strain C57BL/6J (56 days, male) 8.8
70918880 Antisense, RP_050712_04_F12, Mouse strain C57BL/6J (56 days, male) 3.3

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