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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:534.1 nTPM
HPA Brain:583.5 nTPM
GTEx:534.1 nTPM
FANTOM5:900.6 Scaled Tags Per Million
Pig:1726.2 nTPM
Mouse:1422.7 nTPM
Allen mouse:16.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

583.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 445.1
2586 Male, age 75, left hemisphere 775.7
1870 Female, age 42, unknown 524.8
1833 Male, age 53, unknown 510.5
2019 Male, age 18, unknown 473.0
2828 Female, age 72, unknown 415.6
1830 Male, age 51, unknown 412.6
2411 Female, age 72, unknown 406.3
1827 Male, age 72, unknown 389.7
2666 Male, age 74, left hemisphere 311.9
2219 Male, age 76, both hemispheres 230.6
Dorsal raphe nucleus
nTPM: 410.0
2750 Male, age 76, both hemispheres 459.4
1828 Male, age 53, unknown 452.6
2016 Female, age 72, unknown 421.7
2047 Male, age 72, unknown 380.7
2298 Female, age 72, unknown 335.7
Inferior colliculus
nTPM: 571.2
1848 Female, age 42, unknown 655.6
2849 Male, age 72, unknown 578.0
2097 Female, age 72, unknown 575.8
1890 Male, age 53, unknown 475.5
Median raphe nucleus
nTPM: 456.4
2220 Male, age 76, midline 456.4
Periaquaductal grey, anterior
nTPM: 465.2
2502 Female, age 75, unknown 687.9
1947 Male, age 18, unknown 362.9
1795 Male, age 51, unknown 344.8
Periaquaductal grey, dorsal
nTPM: 458.7
2850 Male, age 76, both hemispheres 560.4
2464 Female, age 72, unknown 511.1
1840 Male, age 53, unknown 482.7
1831 Male, age 72, unknown 280.7
Periaquaductal grey, lateral
nTPM: 369.1
2140 Male, age 76, both hemispheres 500.0
2053 Male, age 18, unknown 373.7
2272 Male, age 74, both hemispheres 233.5
Pretectal area
nTPM: 438.6
1817 Female, age 42, unknown 601.6
2667 Female, age 75, unknown 575.7
1816 Male, age 51, unknown 472.5
2316 Male, age 76, right hemisphere 457.7
2407 Male, age 75, both hemispheres 451.2
1815 Male, age 53, unknown 441.1
2007 Male, age 72, unknown 424.8
1944 Female, age 72, unknown 417.9
2825 Male, age 18, unknown 386.0
2224 Female, age 72, unknown 320.4
2273 Male, age 74, both hemispheres 275.9
Red nucleus
nTPM: 583.5
1954 Female, age 42, unknown 834.1
1821 Female, age 72, unknown 753.2
1904 Male, age 53, unknown 696.0
2769 Male, age 72, unknown 681.7
2227 Male, age 72, unknown 670.9
1865 Male, age 51, unknown 599.4
2823 Male, age 76, right hemisphere 540.0
2503 Female, age 72, unknown 537.7
2785 Male, age 18, unknown 522.8
2588 Male, age 74, left hemisphere 435.0
2725 Female, age 75, unknown 375.6
2584 Male, age 75, left hemisphere 355.2
Substantia nigra
nTPM: 459.7
2241 Male, age 72, unknown 607.3
2699 Male, age 18, unknown 544.8
1889 Female, age 72, unknown 531.1
1851 Male, age 51, unknown 506.8
1916 Female, age 42, unknown 506.1
2409 Female, age 72, unknown 432.7
2665 Male, age 74, both hemispheres 393.4
2583 Male, age 75, right hemisphere 385.1
2590 Female, age 75, unknown 359.0
1941 Male, age 53, unknown 330.5
Superior colliculus
nTPM: 426.5
2664 Male, age 75, both hemispheres 535.2
1839 Male, age 51, unknown 472.4
2087 Female, age 72, unknown 439.9
2261 Male, age 18, unknown 434.6
1796 Male, age 53, unknown 411.3
1895 Male, age 76, right hemisphere 409.2
2587 Male, age 74, left hemisphere 403.2
1995 Male, age 72, unknown 402.1
2668 Female, age 75, unknown 383.4
1913 Female, age 42, unknown 373.2
Ventral tegmental area
nTPM: 411.7
2410 Female, age 72, unknown 477.2
1915 Female, age 42, unknown 456.1
2218 Male, age 76, both hemispheres 432.7
2021 Male, age 53, unknown 374.0
1942 Male, age 51, unknown 369.4
2223 Female, age 72, unknown 361.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

534.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 534.1
Samples: 139

Max nTPM: 1685.5
Min nTPM: 108.0
Std nTPM: 267.8
Median nTPM: 481.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1685.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1434.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1426.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1422.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1296.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1162.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1143.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1133.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1089.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 994.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 918.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 909.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 843.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 841.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 838.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 819.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 805.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 798.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 786.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 778.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 762.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 756.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 736.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 727.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 697.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 696.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 686.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 676.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 664.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 663.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 658.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 630.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 627.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 626.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 624.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 620.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 619.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 584.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 582.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 569.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 560.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 557.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 550.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 550.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 549.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 545.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 539.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 538.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 537.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 533.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 532.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 531.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 524.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 523.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 516.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 512.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 508.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 507.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 505.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 504.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 503.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 503.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 502.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 501.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 500.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 499.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 488.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 482.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 482.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 481.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 471.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 466.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 464.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 460.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 459.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 459.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 454.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 452.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 447.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 443.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 443.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 441.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 430.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 428.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 428.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 428.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 412.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 407.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 401.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 399.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 399.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 394.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 386.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 384.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 383.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 383.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 382.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 374.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 368.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 368.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 363.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 363.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 362.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 358.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 357.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 356.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 353.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 352.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 352.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 352.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 343.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 339.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 338.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 334.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 330.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 329.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 321.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 321.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 320.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 319.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 319.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 313.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 309.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 303.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 299.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 297.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 292.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 291.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 271.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 271.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 265.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 258.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 238.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 225.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 202.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 198.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 188.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 172.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 108.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

900.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 900.6
FF:10158-103A5 76 years, female 900.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1726.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 1425.9
Samples: 4

Max nTPM: 2194.7
Min nTPM: 1027.4
Sample A Female 1384.1
Sample B Female 1027.4
Sample C Male 1097.5
Sample D Male 2194.7
Midbrain
nTPM: 1557.3
Samples: 4

Max nTPM: 1802.7
Min nTPM: 1213.0
Sample A Female 1802.7
Sample B Female 1730.8
Sample C Male 1213.0
Sample D Male 1482.5
Periaqueductal gray
nTPM: 1087.2
Samples: 3

Max nTPM: 1468.0
Min nTPM: 849.5
Sample B Female 1468.0
Sample C Male 849.5
Sample D Male 944.0
Superior colliculi
nTPM: 1726.2
Samples: 4

Max nTPM: 2281.0
Min nTPM: 1189.8
Sample A Female 2281.0
Sample B Female 1189.8
Sample C Male 1546.3
Sample D Male 1887.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1422.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 1422.7
Samples: 4

Max nTPM: 1528.4
Min nTPM: 1322.3
Sample A Male 1379.2
Sample B Male 1322.3
Sample C Female 1528.4
Sample D Female 1460.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

16.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.2
67978757 Antisense, RP_040923_01_G08, Mouse strain C57BL/6J (56 days, male) 19.6
74047918 Antisense, RP_051214_02_D03, Mouse strain C57BL/6J (56 days, male) 18.5
74988768 Antisense, RP_060315_05_H12, Mouse strain C57BL/6J (56 days, male) 13.9
70919872 Antisense, RP_050713_02_C01, Mouse strain C57BL/6J (56 days, male) 13.0

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