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PEA15
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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:952.4 nTPM
HPA Brain:948.9 nTPM
GTEx:952.4 nTPM
FANTOM5:980.4 Scaled Tags Per Million
Pig:1115.3 nTPM
Mouse:537.0 nTPM
Allen mouse:11.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

948.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 727.4
2586 Male, age 75, left hemisphere 979.7
2666 Male, age 74, left hemisphere 936.1
1870 Female, age 42, unknown 836.8
2828 Female, age 72, unknown 765.2
2411 Female, age 72, unknown 712.3
1830 Male, age 51, unknown 700.9
1833 Male, age 53, unknown 698.7
1827 Male, age 72, unknown 644.2
2219 Male, age 76, both hemispheres 525.9
2019 Male, age 18, unknown 474.4
Dorsal raphe nucleus
nTPM: 772.3
2750 Male, age 76, both hemispheres 903.2
2047 Male, age 72, unknown 891.2
1828 Male, age 53, unknown 706.6
2016 Female, age 72, unknown 702.4
2298 Female, age 72, unknown 658.2
Inferior colliculus
nTPM: 537.7
2849 Male, age 72, unknown 616.6
1890 Male, age 53, unknown 557.0
1848 Female, age 42, unknown 553.6
2097 Female, age 72, unknown 423.7
Median raphe nucleus
nTPM: 948.9
2220 Male, age 76, midline 948.9
Periaquaductal grey, anterior
nTPM: 658.5
1947 Male, age 18, unknown 683.4
1795 Male, age 51, unknown 666.6
2502 Female, age 75, unknown 625.6
Periaquaductal grey, dorsal
nTPM: 639.7
2850 Male, age 76, both hemispheres 730.6
1840 Male, age 53, unknown 701.3
2464 Female, age 72, unknown 583.8
1831 Male, age 72, unknown 543.2
Periaquaductal grey, lateral
nTPM: 602.6
2053 Male, age 18, unknown 723.8
2140 Male, age 76, both hemispheres 614.1
2272 Male, age 74, both hemispheres 469.9
Pretectal area
nTPM: 543.8
2825 Male, age 18, unknown 753.4
2407 Male, age 75, both hemispheres 615.0
1815 Male, age 53, unknown 583.2
2224 Female, age 72, unknown 580.2
2667 Female, age 75, unknown 580.2
1817 Female, age 42, unknown 529.6
1816 Male, age 51, unknown 527.3
1944 Female, age 72, unknown 486.1
2316 Male, age 76, right hemisphere 448.4
2007 Male, age 72, unknown 440.3
2273 Male, age 74, both hemispheres 438.3
Red nucleus
nTPM: 752.4
2769 Male, age 72, unknown 843.6
1865 Male, age 51, unknown 821.7
1821 Female, age 72, unknown 819.6
2227 Male, age 72, unknown 812.1
1904 Male, age 53, unknown 811.9
2588 Male, age 74, left hemisphere 803.6
2584 Male, age 75, left hemisphere 791.2
1954 Female, age 42, unknown 789.2
2725 Female, age 75, unknown 728.1
2503 Female, age 72, unknown 684.2
2823 Male, age 76, right hemisphere 658.7
2785 Male, age 18, unknown 465.0
Substantia nigra
nTPM: 748.5
2699 Male, age 18, unknown 1019.2
1916 Female, age 42, unknown 922.6
2583 Male, age 75, right hemisphere 826.9
1851 Male, age 51, unknown 805.8
2665 Male, age 74, both hemispheres 760.9
2241 Male, age 72, unknown 737.2
2590 Female, age 75, unknown 625.5
1889 Female, age 72, unknown 614.0
1941 Male, age 53, unknown 605.3
2409 Female, age 72, unknown 567.9
Superior colliculus
nTPM: 594.2
2664 Male, age 75, both hemispheres 795.3
2668 Female, age 75, unknown 684.8
2587 Male, age 74, left hemisphere 671.2
1913 Female, age 42, unknown 615.7
1796 Male, age 53, unknown 595.7
2261 Male, age 18, unknown 569.5
1839 Male, age 51, unknown 564.4
1995 Male, age 72, unknown 550.7
2087 Female, age 72, unknown 474.0
1895 Male, age 76, right hemisphere 420.5
Ventral tegmental area
nTPM: 833.8
2223 Female, age 72, unknown 1290.6
2021 Male, age 53, unknown 782.4
1915 Female, age 42, unknown 753.5
2410 Female, age 72, unknown 747.4
2218 Male, age 76, both hemispheres 718.0
1942 Male, age 51, unknown 711.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

952.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 952.4
Samples: 139

Max nTPM: 1910.4
Min nTPM: 257.5
Std nTPM: 276.4
Median nTPM: 909.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1910.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1707.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1652.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1619.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1597.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1555.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1527.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1492.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1451.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1431.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1427.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1415.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1386.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1361.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1352.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1343.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1320.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1293.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1270.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1230.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1225.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1195.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1192.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1184.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1183.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1180.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1178.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1145.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1141.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1136.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1127.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1118.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1087.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1081.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1080.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1065.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1055.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1053.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1052.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1045.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1044.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1042.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1041.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1036.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1029.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1020.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1019.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1015.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1003.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1003.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1001.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 984.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 976.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 972.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 964.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 959.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 956.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 955.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 952.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 939.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 930.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 929.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 929.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 919.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 919.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 914.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 913.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 911.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 910.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 909.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 903.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 901.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 894.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 893.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 891.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 872.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 866.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 864.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 859.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 847.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 846.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 844.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 840.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 839.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 839.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 836.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 825.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 824.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 821.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 813.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 811.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 808.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 806.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 804.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 800.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 797.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 796.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 794.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 793.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 787.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 786.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 784.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 783.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 781.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 777.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 774.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 765.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 762.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 759.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 759.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 757.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 754.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 750.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 743.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 739.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 733.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 733.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 732.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 727.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 725.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 721.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 717.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 712.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 700.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 698.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 695.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 644.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 632.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 626.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 612.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 598.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 552.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 551.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 531.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 526.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 510.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 427.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 413.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 257.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

980.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 980.4
FF:10158-103A5 76 years, female 980.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1115.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 949.3
Samples: 4

Max nTPM: 1177.9
Min nTPM: 622.7
Sample A Female 1109.5
Sample B Female 622.7
Sample C Male 887.1
Sample D Male 1177.9
Midbrain
nTPM: 1115.3
Samples: 4

Max nTPM: 2574.2
Min nTPM: 497.8
Sample A Female 2574.2
Sample B Female 873.3
Sample C Male 515.8
Sample D Male 497.8
Periaqueductal gray
nTPM: 577.7
Samples: 3

Max nTPM: 648.6
Min nTPM: 536.0
Sample B Female 648.6
Sample C Male 536.0
Sample D Male 548.6
Superior colliculi
nTPM: 670.6
Samples: 4

Max nTPM: 803.6
Min nTPM: 404.8
Sample A Female 803.6
Sample B Female 404.8
Sample C Male 698.7
Sample D Male 775.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

537.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 537.0
Samples: 4

Max nTPM: 554.7
Min nTPM: 519.2
Sample A Male 546.7
Sample B Male 519.2
Sample C Female 527.4
Sample D Female 554.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

11.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.9
68193012 Antisense, RP_040928_01_B12, Mouse strain C57BL/6J (56 days, male) 17.1
70928292 Antisense, RP_050725_02_C07, Mouse strain C57BL/6J (56 days, male) 11.0
77414654 Antisense, RP_070205_01_H12, Mouse strain C57BL/6J (56 days, male) 7.7

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