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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Bowman's capsule:
High
Cells in glomeruli:
Medium
Collecting ducts:
High
Distal tubules:
High
Proximal tubules (cell body):
High
Proximal tubules (microvilli):
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
446.8
nTPM
HPA:
446.8
nTPM
GTEx:
434.5
nTPM
FANTOM5:
467.4
Scaled Tags Per Million
KIDNEY - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA042777
Antibody HPA048459
Bowman's capsule
-
High
Cells in glomeruli
Low
Medium
Cells in tubules
High
-
Collecting ducts
-
High
Distal tubules
-
High
Proximal tubules (cell body)
-
High
Proximal tubules (microvilli)
-
Not detected
KIDNEY - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
446.8
Female, age 58
Kidney sample 55 nTPM: 368.6
Cell types%
Cells in tubules:
60
Cells in glomeruli:
20
Fibroblasts:
5
Other cell types:
15
Female, age 67
Kidney sample 56 nTPM: 372.4
Cell types%
Cells in tubules:
70
Cells in glomeruli:
15
Fibroblasts:
10
Other cell types:
5
Female, age 55
Kidney sample 57 nTPM: 274.6
Cell types%
Cells in tubules:
80
Cells in glomeruli:
10
Fibroblasts:
5
Other cell types:
5
Male, age 46
Kidney sample 58 nTPM: 373.8
Cell types%
Cells in tubules:
60
Cells in glomeruli:
25
Fibroblasts:
5
Other cell types:
10
Female, age 57
Kidney sample 358 nTPM: 573.8
Cell types%
Cells in tubules:
60
Cells in glomeruli:
10
Fibroblasts:
10
Other cell types:
20
Male, age 78
Kidney sample 377 nTPM: 475.2
Cell types%
Cells in tubules:
65
Cells in glomeruli:
10
Fibroblasts:
5
Other cell types:
20
Male, age 73
Kidney sample 380 nTPM: 751.5
Cell types%
Cells in tubules:
60
Cells in glomeruli:
10
Fibroblasts:
10
Other cell types:
20
Female, age 59
Kidney sample 394 nTPM: 345.7
Cell types%
Cells in tubules:
65
Cells in glomeruli:
10
Fibroblasts:
10
Other cell types:
15
Female, age 48
Kidney sample 414 nTPM: 485.2
Cell types%
Cells in tubules:
60
Cells in glomeruli:
5
Fibroblasts:
10
Other cell types:
25
KIDNEY - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
434.5
GTEx sample id
Sample description
nTPM
Kidney - Cortex Average nTPM: 404.0
Samples: 85
Max nTPM: 864.6
Min nTPM: 143.5
Std nTPM: 134.1
Median nTPM: 378.5
GTEX-13NYB-1726-SM-5N9G2
40-49 years, male
864.6
GTEX-14E6D-2526-SM-5YYA9
50-59 years, male
804.5
GTEX-T6MN-1826-SM-EXOHN
50-59 years, male
802.8
GTEX-14C5O-2026-SM-5YYB1
60-69 years, male
658.7
GTEX-1JMPZ-1226-SM-ARU8Y
30-39 years, male
614.9
GTEX-11OF3-1326-SM-5N9FJ
60-69 years, male
608.7
GTEX-ZYT6-2226-SM-5GIC9
30-39 years, male
583.6
GTEX-1NV8Z-2226-SM-EXOJ2
60-69 years, male
578.3
GTEX-O5YV-1226-SM-EV795
60-69 years, female
571.1
GTEX-1R9PO-1626-SM-E6CPT
60-69 years, female
564.6
GTEX-1K9T9-1826-SM-CXZK2
50-59 years, female
562.7
GTEX-1JMQJ-1726-SM-E9U4V
50-59 years, male
552.5
GTEX-1GTWX-1826-SM-9QEHG
60-69 years, male
540.8
GTEX-1KWVE-0826-SM-CXZKO
30-39 years, male
539.9
GTEX-17HHY-2326-SM-7KFSR
50-59 years, male
517.7
GTEX-1PWST-2226-SM-EVR3G
70-79 years, male
509.9
GTEX-Y5V6-2026-SM-5IFHO
60-69 years, male
496.7
GTEX-1C6VQ-2326-SM-7IGN1
50-59 years, male
478.5
GTEX-17F96-1926-SM-7MGWY
70-79 years, male
477.7
GTEX-QDVN-1626-SM-48TZC
50-59 years, male
475.5
GTEX-REY6-1826-SM-EAZAT
60-69 years, male
472.8
GTEX-14C39-2126-SM-664OH
40-49 years, male
472.0
GTEX-T5JC-1526-SM-4DM68
20-29 years, male
461.5
GTEX-1GMR3-2426-SM-7MXV2
40-49 years, male
457.5
GTEX-13RTJ-2226-SM-5S2Q1
60-69 years, male
448.8
GTEX-NPJ8-2226-SM-3TW8D
40-49 years, male
442.9
GTEX-1EKGG-2226-SM-7IGOA
60-69 years, male
438.2
GTEX-13OW6-1826-SM-5N9F9
50-59 years, male
432.6
GTEX-QDT8-1726-SM-EYYV6
30-39 years, female
432.0
GTEX-1GN1U-2126-SM-AHZ4J
50-59 years, female
427.8
GTEX-1GF9W-1326-SM-7P8PX
60-69 years, male
427.6
GTEX-1JMQK-1926-SM-CJI3B
60-69 years, male
427.3
GTEX-1IKK5-0926-SM-A9G2U
60-69 years, male
426.8
GTEX-1J1OQ-1426-SM-AHZ3P
40-49 years, female
423.3
GTEX-1H3NZ-2126-SM-9WPQ6
60-69 years, male
409.4
GTEX-ZYFG-1626-SM-5GZYY
60-69 years, female
406.7
GTEX-P4QS-1126-SM-3NMD5
60-69 years, male
406.4
GTEX-1QP6S-1526-SM-EXUSG
40-49 years, male
404.4
GTEX-1CB4J-1926-SM-7MGX8
60-69 years, male
398.2
GTEX-S33H-1426-SM-EZ6L7
30-39 years, male
394.1
GTEX-1HB9E-1826-SM-D4P33
50-59 years, male
387.7
GTEX-12696-0926-SM-5FQTV
60-69 years, male
387.2
GTEX-1GF9V-1926-SM-9JGHE
60-69 years, male
378.5
GTEX-15CHQ-2126-SM-6871M
60-69 years, male
376.4
GTEX-145MN-0326-SM-5QGQI
30-39 years, male
373.1
GTEX-1HCU7-1826-SM-A9G2A
50-59 years, male
373.0
GTEX-15DYW-2026-SM-6AJBD
60-69 years, female
372.4
GTEX-1BAJH-1826-SM-731DA
70-79 years, male
370.7
GTEX-1LG7Y-2726-SM-D5OVW
50-59 years, male
368.5
GTEX-1497J-0826-SM-5NQAJ
60-69 years, male
352.6
GTEX-1JJ6O-2526-SM-AHZ3J
60-69 years, male
352.1
GTEX-1A8FM-2026-SM-7P8RN
50-59 years, female
351.9
GTEX-QLQW-1626-SM-CMKFE
30-39 years, male
348.9
GTEX-ZC5H-1726-SM-5HL7X
40-49 years, female
343.3
GTEX-13OVL-1826-SM-5KLZR
50-59 years, male
343.0
GTEX-17F97-1926-SM-7IGM4
50-59 years, male
341.2
GTEX-ZDXO-0226-SM-4WKH7
60-69 years, male
339.6
GTEX-1E2YA-1626-SM-7MGXS
50-59 years, male
339.0
GTEX-1HBPI-2026-SM-CE6RZ
50-59 years, male
330.5
GTEX-1F48J-2226-SM-7MXTN
50-59 years, female
330.0
GTEX-12WSG-0826-SM-5EQ5A
50-59 years, female
329.9
GTEX-16MT8-1926-SM-7EPGL
60-69 years, female
327.6
GTEX-1JMLX-1526-SM-AHZ3N
50-59 years, male
325.8
GTEX-Y5V5-1226-SM-EYYVP
60-69 years, female
324.3
GTEX-1N2DW-1826-SM-EAZ54
50-59 years, male
320.6
GTEX-XPVG-0526-SM-4B65N
50-59 years, male
319.9
GTEX-11TTK-1926-SM-5PNW8
60-69 years, female
318.7
GTEX-1H3VY-1926-SM-9JGHJ
50-59 years, male
313.3
GTEX-1OJC4-2326-SM-DTXA5
50-59 years, female
311.6
GTEX-13O1R-2526-SM-5N9FW
60-69 years, male
310.7
GTEX-11GS4-2326-SM-5A5KS
60-69 years, male
304.1
GTEX-1I1GP-1926-SM-CNNQU
50-59 years, male
295.8
GTEX-1MUQO-2526-SM-E9TJN
60-69 years, male
294.4
GTEX-13112-2126-SM-5GCO4
50-59 years, male
281.6
GTEX-1AX8Z-2326-SM-731CR
60-69 years, male
268.6
GTEX-1N2EF-1426-SM-EXUSH
60-69 years, male
267.7
GTEX-ZLFU-0926-SM-5P9F8
40-49 years, male
257.4
GTEX-ZVZP-0926-SM-5GIDB
50-59 years, male
241.0
GTEX-147F4-2626-SM-5Q5CS
50-59 years, male
235.1
GTEX-1IL2V-1826-SM-ARU7R
70-79 years, male
234.3
GTEX-1399S-0526-SM-5IJG8
30-39 years, female
219.1
GTEX-13OVI-1126-SM-5KLZF
60-69 years, female
186.5
GTEX-1A3MW-2226-SM-73KUX
60-69 years, female
177.3
GTEX-ZE9C-1426-SM-4WKGM
60-69 years, male
155.3
GTEX-RN64-1626-SM-48FD7
50-59 years, male
143.5
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Kidney - Medulla Average nTPM: 434.5
Samples: 4
Max nTPM: 713.8
Min nTPM: 302.6
Std nTPM: 164.2
Median nTPM: 360.8
GTEX-RU72-1926-SM-EAZ3F
50-59 years, female
713.8
GTEX-TKQ2-0626-SM-EZ6LB
50-59 years, male
389.4
GTEX-T5JC-1626-SM-EZ6KW
20-29 years, male
332.2
GTEX-R55E-2026-SM-EZ6L1
20-29 years, male
302.6
KIDNEY - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
