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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:309.1 nTPM
HPA Brain:122.6 nTPM
GTEx:309.1 nTPM
FANTOM5:132.7 Scaled Tags Per Million
Pig:8.2 nTPM
Mouse:981.2 nTPM
Allen mouse:9.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

122.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 104.4
1827 Male, age 72, unknown 128.6
2019 Male, age 18, unknown 122.8
2411 Female, age 72, unknown 114.8
1870 Female, age 42, unknown 107.2
1833 Male, age 53, unknown 103.7
2666 Male, age 74, left hemisphere 102.7
2828 Female, age 72, unknown 99.2
2219 Male, age 76, both hemispheres 96.8
1830 Male, age 51, unknown 96.5
2586 Male, age 75, left hemisphere 71.3
Dorsal raphe nucleus
nTPM: 110.9
2298 Female, age 72, unknown 132.2
1828 Male, age 53, unknown 118.0
2750 Male, age 76, both hemispheres 105.2
2047 Male, age 72, unknown 100.1
2016 Female, age 72, unknown 99.2
Inferior colliculus
nTPM: 118.8
2097 Female, age 72, unknown 139.2
1890 Male, age 53, unknown 115.6
1848 Female, age 42, unknown 110.9
2849 Male, age 72, unknown 109.3
Median raphe nucleus
nTPM: 102.8
2220 Male, age 76, midline 102.8
Periaquaductal grey, anterior
nTPM: 110.7
1947 Male, age 18, unknown 119.3
1795 Male, age 51, unknown 112.7
2502 Female, age 75, unknown 100.1
Periaquaductal grey, dorsal
nTPM: 97.1
2850 Male, age 76, both hemispheres 105.0
1840 Male, age 53, unknown 97.4
1831 Male, age 72, unknown 96.0
2464 Female, age 72, unknown 89.9
Periaquaductal grey, lateral
nTPM: 105.7
2272 Male, age 74, both hemispheres 132.9
2053 Male, age 18, unknown 94.3
2140 Male, age 76, both hemispheres 89.9
Pretectal area
nTPM: 122.6
1817 Female, age 42, unknown 156.9
2007 Male, age 72, unknown 143.1
1816 Male, age 51, unknown 142.2
1944 Female, age 72, unknown 132.5
1815 Male, age 53, unknown 128.8
2273 Male, age 74, both hemispheres 127.7
2667 Female, age 75, unknown 123.2
2224 Female, age 72, unknown 112.8
2825 Male, age 18, unknown 103.6
2316 Male, age 76, right hemisphere 96.3
2407 Male, age 75, both hemispheres 81.9
Red nucleus
nTPM: 108.6
1821 Female, age 72, unknown 152.7
2725 Female, age 75, unknown 127.8
2823 Male, age 76, right hemisphere 115.9
1954 Female, age 42, unknown 110.5
2785 Male, age 18, unknown 109.1
2503 Female, age 72, unknown 107.3
2769 Male, age 72, unknown 104.6
2227 Male, age 72, unknown 101.7
2588 Male, age 74, left hemisphere 97.8
1865 Male, age 51, unknown 97.5
1904 Male, age 53, unknown 96.4
2584 Male, age 75, left hemisphere 82.3
Substantia nigra
nTPM: 119.5
1889 Female, age 72, unknown 152.1
1916 Female, age 42, unknown 149.6
1941 Male, age 53, unknown 131.7
1851 Male, age 51, unknown 129.7
2241 Male, age 72, unknown 127.6
2665 Male, age 74, both hemispheres 117.9
2699 Male, age 18, unknown 109.2
2409 Female, age 72, unknown 103.8
2590 Female, age 75, unknown 102.2
2583 Male, age 75, right hemisphere 71.7
Superior colliculus
nTPM: 103.0
2587 Male, age 74, left hemisphere 135.1
1895 Male, age 76, right hemisphere 116.7
2087 Female, age 72, unknown 113.8
1796 Male, age 53, unknown 111.6
2261 Male, age 18, unknown 107.2
2668 Female, age 75, unknown 105.7
1839 Male, age 51, unknown 100.6
1913 Female, age 42, unknown 84.5
1995 Male, age 72, unknown 82.2
2664 Male, age 75, both hemispheres 73.0
Ventral tegmental area
nTPM: 108.5
2218 Male, age 76, both hemispheres 123.9
1915 Female, age 42, unknown 123.2
2410 Female, age 72, unknown 117.6
2223 Female, age 72, unknown 104.7
1942 Male, age 51, unknown 95.8
2021 Male, age 53, unknown 85.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

309.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 309.1
Samples: 139

Max nTPM: 591.7
Min nTPM: 192.7
Std nTPM: 71.1
Median nTPM: 294.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 591.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 514.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 499.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 483.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 468.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 458.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 451.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 451.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 445.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 444.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 434.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 425.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 425.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 419.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 411.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 407.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 392.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 389.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 386.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 386.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 384.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 381.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 373.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 372.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 370.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 366.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 366.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 366.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 362.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 359.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 353.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 352.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 350.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 338.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 338.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 333.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 332.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 332.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 330.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 329.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 328.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 327.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 323.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 323.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 322.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 322.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 322.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 322.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 321.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 319.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 315.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 315.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 313.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 312.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 310.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 309.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 309.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 308.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 304.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 303.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 302.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 302.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 301.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 301.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 298.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 297.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 296.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 295.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 295.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 294.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 294.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 293.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 292.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 291.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 290.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 288.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 288.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 287.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 286.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 285.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 283.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 282.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 281.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 280.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 280.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 280.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 276.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 275.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 275.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 274.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 270.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 267.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 266.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 266.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 265.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 264.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 264.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 264.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 263.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 262.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 259.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 258.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 257.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 256.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 255.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 255.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 254.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 254.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 254.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 253.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 252.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 250.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 250.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 250.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 250.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 249.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 248.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 246.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 246.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 246.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 246.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 241.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 239.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 236.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 232.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 232.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 231.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 229.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 229.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 228.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 227.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 223.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 220.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 218.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 213.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 208.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 205.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 200.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 192.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

132.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 132.7
FF:10158-103A5 76 years, female 132.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

8.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 5.6
Samples: 4

Max nTPM: 7.6
Min nTPM: 1.4
Sample A Female 1.4
Sample B Female 7.2
Sample C Male 6.3
Sample D Male 7.6
Midbrain
nTPM: 6.1
Samples: 4

Max nTPM: 8.0
Min nTPM: 4.2
Sample A Female 4.2
Sample B Female 8.0
Sample C Male 7.0
Sample D Male 5.2
Periaqueductal gray
nTPM: 8.2
Samples: 3

Max nTPM: 8.9
Min nTPM: 7.5
Sample B Female 8.9
Sample C Male 7.5
Sample D Male 8.1
Superior colliculi
nTPM: 5.0
Samples: 4

Max nTPM: 7.7
Min nTPM: 1.4
Sample A Female 1.4
Sample B Female 7.7
Sample C Male 5.2
Sample D Male 5.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

981.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 981.2
Samples: 4

Max nTPM: 1023.1
Min nTPM: 949.1
Sample A Male 1023.1
Sample B Male 949.4
Sample C Female 949.1
Sample D Female 1003.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.8
77371785 Antisense, RP_070116_01_C02, Mouse strain C57BL/6J (56 days, male) 11.0
67765702 Antisense, RP_040916_01_D05, Mouse strain C57BL/6J (56 days, male) 8.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org