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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:52202.8 nTPM
HPA Brain:32973.0 nTPM
GTEx:52202.8 nTPM
Pig:32044.5 nTPM
Mouse:12915.6 nTPM

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32973.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 24067.7
2586 Male, age 75, left hemisphere 41399.8
2219 Male, age 76, both hemispheres 34436.3
2666 Male, age 74, left hemisphere 34179.2
1870 Female, age 42, unknown 26227.8
1833 Male, age 53, unknown 23349.6
2828 Female, age 72, unknown 21121.8
1830 Male, age 51, unknown 19394.0
1827 Male, age 72, unknown 13994.2
2019 Male, age 18, unknown 13795.8
2411 Female, age 72, unknown 12778.8
Dorsal raphe nucleus
nTPM: 14782.6
1828 Male, age 53, unknown 20908.7
2047 Male, age 72, unknown 18716.2
2750 Male, age 76, both hemispheres 15883.2
2016 Female, age 72, unknown 13435.0
2298 Female, age 72, unknown 4969.9
Inferior colliculus
nTPM: 22832.1
2849 Male, age 72, unknown 42735.0
1890 Male, age 53, unknown 22299.2
1848 Female, age 42, unknown 18675.1
2097 Female, age 72, unknown 7619.0
Median raphe nucleus
nTPM: 32973.0
2220 Male, age 76, midline 32973.0
Periaquaductal grey, anterior
nTPM: 13084.8
2502 Female, age 75, unknown 14819.3
1795 Male, age 51, unknown 13833.2
1947 Male, age 18, unknown 10602.0
Periaquaductal grey, dorsal
nTPM: 22691.8
2850 Male, age 76, both hemispheres 42849.5
2464 Female, age 72, unknown 17377.2
1840 Male, age 53, unknown 15418.0
1831 Male, age 72, unknown 15122.6
Periaquaductal grey, lateral
nTPM: 11628.0
2140 Male, age 76, both hemispheres 16314.8
2053 Male, age 18, unknown 12488.2
2272 Male, age 74, both hemispheres 6080.9
Pretectal area
nTPM: 17887.9
2667 Female, age 75, unknown 29684.7
1944 Female, age 72, unknown 24920.5
1817 Female, age 42, unknown 21941.6
1816 Male, age 51, unknown 21619.9
2007 Male, age 72, unknown 21346.5
1815 Male, age 53, unknown 20190.4
2825 Male, age 18, unknown 18506.5
2407 Male, age 75, both hemispheres 15000.4
2224 Female, age 72, unknown 9396.1
2316 Male, age 76, right hemisphere 8199.7
2273 Male, age 74, both hemispheres 5960.8
Red nucleus
nTPM: 22862.8
2503 Female, age 72, unknown 29433.5
1865 Male, age 51, unknown 29145.4
2588 Male, age 74, left hemisphere 28435.0
2584 Male, age 75, left hemisphere 28327.0
1954 Female, age 42, unknown 23592.4
2823 Male, age 76, right hemisphere 22905.4
2725 Female, age 75, unknown 21209.1
2785 Male, age 18, unknown 19832.7
2769 Male, age 72, unknown 19755.2
2227 Male, age 72, unknown 19385.0
1904 Male, age 53, unknown 19131.3
1821 Female, age 72, unknown 13201.8
Substantia nigra
nTPM: 24586.6
2699 Male, age 18, unknown 55435.9
2665 Male, age 74, both hemispheres 42221.2
1916 Female, age 42, unknown 30598.9
1941 Male, age 53, unknown 20802.3
1889 Female, age 72, unknown 19621.7
2583 Male, age 75, right hemisphere 18840.0
2241 Male, age 72, unknown 16343.9
2409 Female, age 72, unknown 15324.3
1851 Male, age 51, unknown 14778.6
2590 Female, age 75, unknown 11899.0
Superior colliculus
nTPM: 17844.0
2664 Male, age 75, both hemispheres 32756.8
2587 Male, age 74, left hemisphere 21026.2
2087 Female, age 72, unknown 19631.9
1913 Female, age 42, unknown 17762.3
1895 Male, age 76, right hemisphere 15779.6
2668 Female, age 75, unknown 15685.2
1839 Male, age 51, unknown 15482.9
1995 Male, age 72, unknown 15384.4
1796 Male, age 53, unknown 13718.3
2261 Male, age 18, unknown 11212.5
Ventral tegmental area
nTPM: 19166.8
2218 Male, age 76, both hemispheres 28821.1
2223 Female, age 72, unknown 22105.4
1942 Male, age 51, unknown 18627.7
1915 Female, age 42, unknown 15941.2
2021 Male, age 53, unknown 15654.3
2410 Female, age 72, unknown 13851.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

52202.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 52202.8
Samples: 139

Max nTPM: 214792.6
Min nTPM: 7057.4
Std nTPM: 40361.8
Median nTPM: 39359.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 214792.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 204972.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 170941.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 153749.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 150729.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 135400.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 134324.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 133997.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 132158.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 126923.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 126198.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 126013.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 118009.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 116752.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 114293.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 113817.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 112966.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 103848.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 102517.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 92363.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 88674.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 88157.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 85791.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 84956.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 82400.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 79286.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 76324.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 75758.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 75412.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 75280.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 73820.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 72095.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 72028.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 71004.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 66719.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 66616.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 66210.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 64956.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 64847.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 64766.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 62760.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 58575.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 57858.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 57227.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 56522.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 56420.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 53935.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 51711.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 50168.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 48812.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 48719.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 47359.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 46675.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 46531.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 46422.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 46069.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 46016.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 44983.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 44496.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 44273.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 43427.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 42981.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 42758.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 41314.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 41045.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 40038.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 39881.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 39473.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 39469.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 39359.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 38931.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 38174.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 36950.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 36907.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 35722.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 35322.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 35278.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 35266.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 34726.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 34011.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 33925.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 33828.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 33653.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 31666.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 31350.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 30632.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 29938.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 29369.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 29279.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 28222.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 27190.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 27030.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 26664.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 26653.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 26464.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 26200.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 25937.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 25770.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 24606.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 24566.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 24465.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 24367.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 24292.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 24275.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 23633.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 23465.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 23030.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 22371.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 22239.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 21687.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 21136.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 20751.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 20649.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 20309.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 20265.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 20190.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 20184.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 19963.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 19925.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 19871.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 19740.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 19475.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 19404.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 18770.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 18015.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 17703.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 17087.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 16368.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 15940.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 15608.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 14802.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 14390.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 12679.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 12408.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 11619.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 11380.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 9220.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 8032.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 7057.4
Show allShow less

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32044.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 26141.5
Samples: 4

Max nTPM: 30954.6
Min nTPM: 19189.8
Sample A Female 30954.6
Sample B Female 24972.6
Sample C Male 29448.8
Sample D Male 19189.8
Midbrain
nTPM: 32044.5
Samples: 4

Max nTPM: 42907.6
Min nTPM: 24480.2
Sample A Female 24480.2
Sample B Female 42907.6
Sample C Male 33715.4
Sample D Male 27074.7
Periaqueductal gray
nTPM: 22474.5
Samples: 3

Max nTPM: 24407.7
Min nTPM: 20546.4
Sample B Female 24407.7
Sample C Male 22469.5
Sample D Male 20546.4
Superior colliculi
nTPM: 26769.5
Samples: 4

Max nTPM: 34645.4
Min nTPM: 11038.6
Sample A Female 28214.7
Sample B Female 11038.6
Sample C Male 34645.4
Sample D Male 33179.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12915.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 12915.6
Samples: 4

Max nTPM: 14449.2
Min nTPM: 12168.1
Sample A Male 14449.2
Sample B Male 12594.0
Sample C Female 12168.1
Sample D Female 12450.9

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