Prostate cancer is one of the most common malignancies in men worldwide with more than 300,000 new cases estimated in USA in 2025. The cancer develops in the prostate gland with the most common form being adenocarcinoma that originate from the glandular cells in the prostate and accounts for more than 95% of the cases.

The tumor is usually slow growing but can become aggressive and spread. Early detection significantly improves outcome, and awareness is therefore of major importance.

Movember is a hybrid word of moustache and November, and an annual event to raise awareness of men's health issues focusing on prostate cancer, testicular cancer and suicide. The events run by the Movember Foundation charity aim to increase early cancer detection, diagnosis and effective treatments, and ultimately reduce the number of preventable deaths.

The Human Protein Atlas Cancer resource presents IHC images and transcriptomics data for 480 prostate adenocarcinomas together with Kaplan-Meier plots showing the correlation between mRNA expression of each human gene and cancer patient survival. In total 172 genes are suggested to be prognostic of which 18 are associated with favorable prognosis and 154 with unfavorable.

Cell line models are frequently used for cancer studies and based on correlation analysis between the expression profiles of cell lines and their corresponding TCGA disease cohort in the Cell line resource the cell line VCaP would be the most suitable choice for studying prostate adenocarcinoma.

Read more about prostate cancer in HPA