The version 25 of the Human Protein Atlas has been launched with lots of additional data and new features. Data corresponding to all human protein-coding genes is presented in 9 different resources including protein profiles in cells, tissues, organs and blood. The open access resource now includes more than 10 million manually annotated bioimages and data for over 6 billion assay measurements from 300,000 separate biological samples.

A major new feature is the Olink HT and SomaScan blood profiling data across 32 cohorts, including different diseases and healthy cohorts reflecting childhood development, aging and pregnancy, that has been added to the Blood resource. The resource now displays pan-disease data for 71 different cohorts.

The Interaction resource has been extended with "in-house" generated AlphaFold 3 predicted 3D structures for 23000 protein-protein interactions.

Four new tissues have been added to the Single cell resource and and several of the old datasets have been replaced to improve quality and cell type representation. The resource now includes 154 different cell types which represent the majority of all cell types in the human body.

Also the Tissue resource has been extended with eight new tissues in addition to a new pancreas antibody panel used for multiplex tissue profiling.

Link to press release

Link to launch webinar